Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length55 amino acids

Chemical FormulaC261H422N64O85S4

DescriptionStandard

        MENVCEKVTNSVSSELQPYFQTLPVMTKIDAVAGINYGLVAPPATTAETLDVQMK
    

Molecular Weight5944.78 Da

Isoelectric Point (pI)4.36

Net Charge (pH 7.0)-3.50

Net Charge (pH 7.4) -3.75

Charge Density (pH 7.0) -0.0637

GRAVY Index0.06

Hydrophobic Moment 0.52

Boman Index0.15

Instability Index32.79

Aliphatic Index 88.55

Aromaticity 0.0545

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2382.49

LogP -24.36

H-bond Donors 79.0

H-bond Acceptors 86.0

Rotatable Bonds 192.0

Heavy Atoms 414.0

Ring Count 7.0

Amide Bonds 60.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0191065 VERIFIED: NO

Provenance & Taxonomy

OrganismPongo abelii [Bacterium]

FamilyBPI

Tax ID9601

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin Non-hemolytic

TargetGram-negative bacteria

MethodQualitative functional evidence

RECORD: Rec_0196316 VERIFIED: NO