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MYP_084982
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Basic Information
YFGAP-NH2(Yellowfin tuna GAPDH-related antimicrobial peptide; fish, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
32 amino acids
C154H258N48O40
Standard
Sequence
VKVGINGFGRIGRLVTRAAFHGKKVEVVAIND
Physicochemical Analysis
3421.99 Da
11.00
3.83
3.56
0.1195
0.26
0.92
0.08
-15.07
112.50
0.0625
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1438.87
-13.14
51.0
45.0
117.0
242.0
3.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0224394 VERIFIED: YES
Provenance & Taxonomy
Thunnus albacares [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus RM4220
125 μg/mL
MIC
PMID22771964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22771964/
RECORD: Rec_0229837 VERIFIED: YES
Provenance & Taxonomy
Thunnus albacares [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Shigella flexneri KCTC 2517
5 μg/mL
MIC
PMID22771964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22771964/
RECORD: Rec_0229881 VERIFIED: YES
Provenance & Taxonomy
Thunnus albacares [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli KCTC 1116
5 μg/mL
MIC
PMID22771964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22771964/
RECORD: Rec_0230628 VERIFIED: YES
Provenance & Taxonomy
Thunnus albacares [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ML35p
0.4 μg/mL
MEC
PMID22771964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22771964/
RECORD: Rec_0234228 VERIFIED: YES
Provenance & Taxonomy
Thunnus albacares [Animal]
8236.0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Hemolytic Antimicrobial
Human erythrocytes
100000 μg/mL
Hemolysis
PaperSeo JK, Lee MJ, Go HJ, et al. Purification and characterization of YFGAP, a GAPDH-related novel antimicrobial peptide, from the skin of yellowfin tuna, Thunnus albacares. Fish Shellfish Immunol. 2012 Oct;33(4):743-752. doi:10.1016/j.fsi.2012.06.023. PMID22771964 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22771964/
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