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MYP_084970
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Basic Information
Mini-ChBac7.5N beta
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
21 amino acids
C118H212N54O22
Standard
Sequence
RRLRPRRPRLPRPRPRPRPRP
Physicochemical Analysis
2739.29 Da
12.00
10.76
10.56
0.5124
-2.60
0.38
-1.18
121.49
37.14
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1255.90
-12.87
47.0
33.0
81.0
194.0
8.0
20.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0066333 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli (ML35p)
0.3 ± 0.1μM without NaCl;MIC=1.4 ± 0.2μM 100 mM NaCl;MIC=1μM Broth microdilution assay
MIC
PMID27795854 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27795854/
RECORD: Rec_0095586 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
S-aureus ATCC 25923 or 710A or MRSA
>64 μM
MIC
PaperMinibactenecins ChBac7.Nalpha and ChBac7. Nbeta - Antimicrobial Peptides from Leukocytes of the Goat Capra hircus
RECORD: Rec_0108787 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
clinical isolate
4 μM Broth microdilution assay
MIC
PMID27795854 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27795854/
RECORD: Rec_0108890 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Candida albicans (820)
0.3 ± 0.1μM without NaCl;MIC> 50μM 100 mM NaCl;MIC=64μM Broth microdilution assay
MIC
PMID27795854 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27795854/
RECORD: Rec_0109165 VERIFIED: YES
Provenance & Taxonomy
Capra hircus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli (ATCC 25922)
0.5 ± 0.2μM without NaCl;MIC=0.8 ± 0.2μM 100 mM NaCl;MIC=2μM Broth microdilution assay
MIC
PMID27795854 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27795854/
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