Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC360H582N100O90S8

DescriptionStandard

        MKLLLLTLTVLLLLSQLTPGDTQRCWNLYGKCRHRCSRKERVYVYCLNNKMCCVKPKYQPKEKWGPF
    

Molecular Weight8007.61 Da

Isoelectric Point (pI)9.70

Net Charge (pH 7.0)9.52

Net Charge (pH 7.4) 9.15

Charge Density (pH 7.0) 0.1421

GRAVY Index-0.35

Hydrophobic Moment 0.48

Boman Index-0.11

Instability Index27.23

Aliphatic Index 87.16

Aromaticity 0.1045

Extinction Coeff. Reduced 16960.00

Extinction Coeff. Oxidized 17335.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3099.42

LogP -22.49

H-bond Donors 115.0

H-bond Acceptors 109.0

Rotatable Bonds 266.0

Heavy Atoms 558.0

Ring Count 14.0

Amide Bonds 72.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0280142 VERIFIED: NO

Provenance & Taxonomy

OrganismChlorocebus sabaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID60711

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic