Peptide Database

Peptide NameBovine Beta-defensin 2

Function Ontology

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Standard StatusStandard

Sequence Length38 amino acids

Chemical FormulaC185H314N68O44S6

DescriptionStandard

        VRNFVTCRINRGFCVPIRCPGHRRQIGTCLGPRIKCCR
    

Molecular Weight4387.29 Da

Isoelectric Point (pI)11.20

Net Charge (pH 7.0)8.76

Net Charge (pH 7.4) 8.41

Charge Density (pH 7.0) 0.2305

GRAVY Index-0.17

Hydrophobic Moment 0.76

Boman Index-0.22

Instability Index31.47

Aliphatic Index 74.21

Aromaticity 0.0526

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 375.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1833.28

LogP -20.38

H-bond Donors 73.0

H-bond Acceptors 60.0

Rotatable Bonds 142.0

Heavy Atoms 303.0

Ring Count 6.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0235681 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)