Peptide Database

Peptide NamePreprocathelicidin antimicrobial peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length199 amino acids

Chemical FormulaC955H1521N267O308S13

DescriptionStandard

        METQMASPSLGRCSLWLLLLGLLLPSASAQALSYREAVLRAVGQLNEKSSEVNLYRLLELDPPPKDAEDQGARKPVSFRVKETVCPRMSQQPPEQCDFKENGLVKQCVGTVSLDTSNDEFDLNCNEVEDWGARKPASFRVKETVCPRMTQQPPEQCDFKENGLVKQCVGTVSLDPSNDQFDLNCNEGGEKPSYLHPSLP
    

Molecular Weight22087.74 Da

Isoelectric Point (pI)4.80

Net Charge (pH 7.0)-8.45

Net Charge (pH 7.4) -8.91

Charge Density (pH 7.0) -0.0425

GRAVY Index-0.55

Hydrophobic Moment 0.61

Boman Index-0.09

Instability Index34.26

Aliphatic Index 73.92

Aromaticity 0.0553

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15970.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 9260.15

LogP -123.43

H-bond Donors 315.0

H-bond Acceptors 314.0

Rotatable Bonds 717.0

Heavy Atoms 1543.0

Ring Count 31.0

Amide Bonds 221.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0296270 VERIFIED: NO

Provenance & Taxonomy

OrganismOvis aries [Animal]

FamilyCathelicidin

Tax ID9940

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal