Peptide Database

Peptide NameTheta defensin subunit C (BTD-c) (BTD-4 subunit 2)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length76 amino acids

Chemical FormulaC357H587N107O108S6

DescriptionStandard

        MRTFAFLTAMLLLVALHAQAEARQARADEAAIQEQPGADDQGMAHSFTRNESAVLPLSESERGLRCICLLGICRLL
    

Molecular Weight8298.52 Da

Isoelectric Point (pI)5.53

Net Charge (pH 7.0)-2.33

Net Charge (pH 7.4) -2.71

Charge Density (pH 7.0) -0.0307

GRAVY Index0.16

Hydrophobic Moment 0.66

Boman Index0.05

Instability Index34.92

Aliphatic Index 101.71

Aromaticity 0.0395

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3454.75

LogP -34.96

H-bond Donors 123.0

H-bond Acceptors 114.0

Rotatable Bonds 279.0

Heavy Atoms 578.0

Ring Count 7.0

Amide Bonds 81.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004832 VERIFIED: YES

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9555

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetStaphylococcus aureus (Gram-positive)

RECORD: Rec_0014666 VERIFIED: YES

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9555

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetCandida albicans

RECORD: Rec_0101774 VERIFIED: YES

Provenance & Taxonomy

OrganismPapio anubis [Animal]

FamilyAlpha-defensin; Defensin

Tax ID9555

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Non-hemolytic

TargetEscherichia coli (Gram-negative)