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MYP_084898
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Basic Information
BacSP222 (bacteriocin)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Staphylococcus aureus
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
50 amino acids
C276H418N74O68S
Standard
Sequence
MAGLLRFLLSKGRALYNWAKSHVGKVWEWLKSGATYEQIKEWIENALGWR
Physicochemical Analysis
5892.79 Da
9.87
3.59
3.31
0.0718
-0.30
0.58
0.06
9.21
91.80
0.1600
30480.00
30480.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2312.50
-13.12
84.0
74.0
195.0
419.0
14.0
52.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0092403 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus pseudintermedius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus intermedius ATCC 29663
2.00±0.00 μM
MIC
PMID26411997 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26411997/
RECORD: Rec_0125825 VERIFIED: NO
Provenance & Taxonomy
Staphylococcus pseudintermedius [Bacterium]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus
1.00±0.36 μM
MIC
RECORD: Rec_0133765 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus pseudintermedius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus ATCC 25923
1.00± 0.36 μM
MIC
PMID26411997 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26411997/
RECORD: Rec_0146188 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus pseudintermedius strain 222 [Bacterium]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Formylation
Lys11 and Lys20 succinylation
Bio-Activity Profile
Antimicrobial Antibacterial
Bacillus subtilis ATCC 6633
32.66±6.78 %
Radial diffusion assay
PMID34200765 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/34200765/
RECORD: Rec_0153516 VERIFIED: YES
Provenance & Taxonomy
Staphylococcus pseudintermedius [Bacterium]
Bacteriocin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Streptococcus pyogenes PCM 465
7.80± 1.92 μM
MIC
PMID26411997 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26411997/
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