Peptide Database

Peptide NameBacteriocin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length41 amino acids

Chemical FormulaC203H315N53O65S2

DescriptionStandard

        TSYGNGVHCNKSKCWIDVSELETYKAGTVSNPKDILWSLKE
    

Molecular Weight4602.12 Da

Isoelectric Point (pI)6.45

Net Charge (pH 7.0)-0.53

Net Charge (pH 7.4) -0.82

Charge Density (pH 7.0) -0.0128

GRAVY Index-0.59

Hydrophobic Moment 0.39

Boman Index-0.03

Instability Index23.83

Aliphatic Index 71.22

Aromaticity 0.0976

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14105.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1926.96

LogP -20.50

H-bond Donors 69.0

H-bond Acceptors 68.0

Rotatable Bonds 152.0

Heavy Atoms 323.0

Ring Count 8.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0243460 VERIFIED: YES

Provenance & Taxonomy

OrganismLactococcus sp. [Bacterium]

FamilyBacteriocin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli Gj137

RECORD: Rec_0245424 VERIFIED: YES

Provenance & Taxonomy

OrganismLactococcus sp. [Bacterium]

FamilyBacteriocin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetEscherichia coli KL16

RECORD: Rec_0251124 VERIFIED: YES

Provenance & Taxonomy

OrganismLactococcus sp [Bacterium]

FamilyBacteriocin

Structure & Mods

Configtopology not specified [Not included yet]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStreptococcus aureus

RECORD: Rec_0320182 VERIFIED: YES

Provenance & Taxonomy

OrganismLactococcus sp. [Bacterium]

FamilyBacteriocin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetKlebsiella sp.

RECORD: Rec_0347560 VERIFIED: NO

Provenance & Taxonomy

OrganismLactococcus sp [Bacterium]

FamilyBacteriocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetB.thuringiensis, Escherichia coli, Klebsiella sp, Staphylococcus aureus, S.typhi

MethodQualitative functional evidence

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