Peptide Database

Peptide NameMaximins 9 H3 [Cleaved into: Maximin-9; Maximin-H3]

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC716H1167N207O214S4

DescriptionStandard

        MNFKYIVAVSFLIASAYARSVKNDEQSLSQRDVLEEESLREIRGIGRKFLGGVKTTFRCGVKDFASKHLYGKRTAEEHEVMKRLEAIMRDLDSLDHPEEASERETRGFNQDEIANLFTKKEKRILGPVLGLVGNALGGLIKKIG
    

Molecular Weight16227.44 Da

Isoelectric Point (pI)9.01

Net Charge (pH 7.0)2.79

Net Charge (pH 7.4) 2.35

Charge Density (pH 7.0) 0.0193

GRAVY Index-0.42

Hydrophobic Moment 0.90

Boman Index-0.10

Instability Index41.14

Aliphatic Index 90.07

Aromaticity 0.0694

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6883.37

LogP -66.08

H-bond Donors 243.0

H-bond Acceptors 224.0

Rotatable Bonds 570.0

Heavy Atoms 1141.0

Ring Count 15.0

Amide Bonds 151.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0120901 VERIFIED: YES

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyBombinin; Maximin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Defense peptide Antimicrobial Antibiotic Antifungal Anti-Candida Anti-Gram-negative Anti-Gram-positive Cytolytic Hemolytic

TargetGram Negative Bacteria and Gram Positive Bacteria