Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length453 amino acids

Chemical FormulaC2262H3554N618O633S10

DescriptionStandard

        TNPGFVVRITQAGLDYAHQQGVAVLEQELAQLKLPDISGDFRIRHVGKVHYEISSLDLRSFHLPYSRISLVPSVGLQVSISNAFAEVDGNWRVKLHFIRDHGSFDLKVENVYIKINLQLGSDASGKPTADTSNCSTRISKVRVHFSGKFGWLYNLFHRAIEPAFRRTLEAEVCQIVVKSVRSELQPYLRTLPVTARIDARAGIDYSLVAPPTATAQSLDVDLKGEFFSLAHRSTVPFAPLPLAFPPDHDRMVYFGASSYFFNTAGLAYHGAGALVFEITDSMIPKGVEFHLNTTTFSAFIPQLEKMYPDMLMKLRLSAPSAPFLDIGPGGVSLRPVVDIQAYAILPNSSLAPLFLLSLVSNVSAVMDVKSSHIVGSLKVGRYGGGAARGSARPVRMLQSIMNIYASNILLPRLNARLDEGFPLPLPDRIQLSNILLRFHQVSEGQHPARLEPA
    

Molecular Weight49854.83 Da

Isoelectric Point (pI)9.17

Net Charge (pH 7.0)6.73

Net Charge (pH 7.4) 5.66

Charge Density (pH 7.0) 0.0148

GRAVY Index0.06

Hydrophobic Moment 0.83

Boman Index0.11

Instability Index40.86

Aliphatic Index 100.31

Aromaticity 0.0905

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 31985.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0358256 VERIFIED: NO

Provenance & Taxonomy

OrganismGlaucidium brasilianum [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria