Peptide Database

Peptide NameEsculentin-1Pc

Function Ontology

Antimicrobial

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length84 amino acids

Chemical FormulaC409H699N109O124S5

DescriptionStandard

        MFTLKKSLLLIVLLGIISLSLCEQERNADEDEESETKRGLFTKINKKKAKTGVFNIIKTIGKEAGMDVIRAGIDTISCKIKGEC
    

Molecular Weight9287.91 Da

Isoelectric Point (pI)8.84

Net Charge (pH 7.0)2.49

Net Charge (pH 7.4) 2.19

Charge Density (pH 7.0) 0.0296

GRAVY Index-0.05

Hydrophobic Moment 0.67

Boman Index0.00

Instability Index31.91

Aliphatic Index 107.98

Aromaticity 0.0357

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3819.05

LogP -34.66

H-bond Donors 136.0

H-bond Acceptors 132.0

Rotatable Bonds 337.0

Heavy Atoms 647.0

Ring Count 3.0

Amide Bonds 87.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0292364 VERIFIED: YES

Provenance & Taxonomy

OrganismLithobates pipiens [Animal]

Tax ID8404

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antimicrobial Non-hemolytic Non-ribosomal