Peptide Database

Peptide NameSLAY-screened peptide P271

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC99H153N21O27S

DescriptionStandard

        IPPQCPGILLPAYAFSVDSI
    

Molecular Weight2101.46 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-1.25

Net Charge (pH 7.4) -1.47

Charge Density (pH 7.0) -0.0625

GRAVY Index0.88

Hydrophobic Moment 0.20

Boman Index0.46

Instability Index71.78

Aliphatic Index 122.00

Aromaticity 0.1000

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 722.14

LogP -3.96

H-bond Donors 23.0

H-bond Acceptors 27.0

Rotatable Bonds 58.0

Heavy Atoms 148.0

Ring Count 6.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0243915 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Anti-Gram-negative Antimicrobial Antibacterial

TargetEscherichia coli

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/