Peptide Database

Peptide NameC-terminal Filaggrin-2 derived peptide

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC128H186N44O44

DescriptionStandard

        QSHGSSQRVRHGSYGSAEYNYGRSGYGP
    

Molecular Weight3045.11 Da

Isoelectric Point (pI)9.52

Net Charge (pH 7.0)1.93

Net Charge (pH 7.4) 1.62

Charge Density (pH 7.0) 0.0690

GRAVY Index-1.50

Hydrophobic Moment 0.32

Boman Index-0.25

Instability Index42.13

Aliphatic Index 13.93

Aromaticity 0.1429

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1452.16

LogP -22.80

H-bond Donors 53.0

H-bond Acceptors 48.0

Rotatable Bonds 96.0

Heavy Atoms 216.0

Ring Count 7.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0032447 VERIFIED: YES

Provenance & Taxonomy

OrganismRousettus aegyptiacus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)