Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length469 amino acids

Chemical FormulaC2338H3686N592O649S13

DescriptionStandard

        MLWFLVVLLGVGTEAVTPGIKMKITLKGLDYGKQIGMEFLKFALLQLPIPDFRGSYSVPLVGQVEYAVTGFQVKTIDLGESLVAFAPSSRIKLSMGPAEAQVDGHWSVKVSLIHDSGTFKLSVGDMMLAVLVEVGWDGAGRLVVSPAGCSCLIGHLGITFHGGASWLYNIFTGALEHPLRQEFGNKLCKEIQNAVEALERKLQAIPESSHISSVADLDYSLVAPPLITEQNIELDLKGEFYSRLGHKEAPVPPAPFSLWEQNDCMLLLAFSDFVANSAAFVYYGAGALSWNLTDSTVPKKFPIHINTKIFKGLAPELLKRFPDTPMALQLFARRPPRLQTQPGTLQLLLPGAVQAYVLPNGTSAVPVFLLHVDAEASAQVFISGKNIGASLKLTNVSLTLAHSDVGPFLVDRMETLLYVALKSAILPRINRKLKEGFPLPTLPKTTLQDTAINIQEGFLVIATNVQYGA
    

Molecular Weight50888.70 Da

Isoelectric Point (pI)6.56

Net Charge (pH 7.0)-1.62

Net Charge (pH 7.4) -2.50

Charge Density (pH 7.0) -0.0035

GRAVY Index0.26

Hydrophobic Moment 0.78

Boman Index0.20

Instability Index37.57

Aliphatic Index 107.91

Aromaticity 0.0874

Extinction Coeff. Reduced 49390.00

Extinction Coeff. Oxidized 49640.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0183405 VERIFIED: NO

Provenance & Taxonomy

OrganismPhascolarctos cinereus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria