Peptide Database

Peptide NameGlucagon-like peptide 2

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Metabolic

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC173H262N44O56

DescriptionStandard

        HADGTFTSDYNQLLDDIATQEFLKWLINQKVTQ
    

Molecular Weight3854.19 Da

Isoelectric Point (pI)4.35

Net Charge (pH 7.0)-3.15

Net Charge (pH 7.4) -3.41

Charge Density (pH 7.0) -0.0954

GRAVY Index-0.55

Hydrophobic Moment 0.49

Boman Index0.01

Instability Index1.01

Aliphatic Index 85.76

Aromaticity 0.1212

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1657.45

LogP -16.01

H-bond Donors 55.0

H-bond Acceptors 54.0

Rotatable Bonds 128.0

Heavy Atoms 273.0

Ring Count 6.0

Amide Bonds 38.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0093032 VERIFIED: NO

Provenance & Taxonomy

OrganismHeloderma suspectum [Animal]

FamilyGlucagon

Tax ID8554

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Metabolic

RECORD: Rec_0212978 VERIFIED: NO

Provenance & Taxonomy

OrganismHeloderma suspectum [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone

RECORD: Rec_0227748 VERIFIED: YES

Provenance & Taxonomy

OrganismHeloderma suspectum [Animal]

FamilyGlucagon-like peptide

Tax ID8554

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Hormone Endocrine Metabolic regulation Physiological regulation

Half-LifeMammalian: 3.5 hour; Yeast: 10 min; E. coli: >10 hour

RECORD: Rec_0421408 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/