Peptide Database

Peptide NameVigno 1

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC116H185N35O39S6

DescriptionStandard

        GLPLCGETCAGGTCNTPGCSCSWPVCVRN
    

Molecular Weight2886.31 Da

Isoelectric Point (pI)5.96

Net Charge (pH 7.0)-0.30

Net Charge (pH 7.4) -0.59

Charge Density (pH 7.0) -0.0102

GRAVY Index0.22

Hydrophobic Moment 0.28

Boman Index0.17

Instability Index31.63

Aliphatic Index 50.34

Aromaticity 0.0345

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5875.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1154.07

LogP -17.62

H-bond Donors 45.0

H-bond Acceptors 45.0

Rotatable Bonds 84.0

Heavy Atoms 196.0

Ring Count 5.0

Amide Bonds 30.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0321236 VERIFIED: YES

Provenance & Taxonomy

OrganismViola ignobilis [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide scaffold [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

DisulfideCysteine-rich scaffold consistent with multiple disulfide bonds in the annotated family

Bio-Activity Profile

Function

Enzyme inhibitory Enzyme-inhibitory ACE inhibitory Antihypertensive

TargetAngiotensin-converting enzyme