Peptide Database

Peptide NameDybowskin-3 , Brevinin-2DYc

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC147H254N40O42S2

DescriptionStandard

        GLFDVVKGVLKGVGKNVAGSLLEQLKCKLSGGC
    

Molecular Weight3317.96 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.0830

GRAVY Index0.47

Hydrophobic Moment 0.64

Boman Index0.19

Instability Index4.13

Aliphatic Index 117.88

Aromaticity 0.0303

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1325.86

LogP -12.88

H-bond Donors 47.0

H-bond Acceptors 47.0

Rotatable Bonds 118.0

Heavy Atoms 231.0

Ring Count 1.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0420733 VERIFIED: YES

Provenance & Taxonomy

OrganismRana dybowskii [Animal]

Structure & Mods

Configlinear peptide with intramolecular disulfide-stabilized loop [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-Term-

Disulfide27-33

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetBacillus subtilis ATCC 6633

Activity60 μg/mL

MethodMIC

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