Peptide Database

Peptide NameDybowskin-3 , Brevinin-2DYc

Function Ontology

Anticancer

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC147H254N40O42S2

DescriptionStandard

        GLFDVVKGVLKGVGKNVAGSLLEQLKCKLSGGC
    

Molecular Weight3317.96 Da

Isoelectric Point (pI)9.24

Net Charge (pH 7.0)2.74

Net Charge (pH 7.4) 2.50

Charge Density (pH 7.0) 0.0830

GRAVY Index0.47

Hydrophobic Moment 0.64

Boman Index0.19

Instability Index4.13

Aliphatic Index 117.88

Aromaticity 0.0303

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1325.86

LogP -12.88

H-bond Donors 47.0

H-bond Acceptors 47.0

Rotatable Bonds 118.0

Heavy Atoms 231.0

Ring Count 1.0

Amide Bonds 34.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0302905 VERIFIED: YES

Provenance & Taxonomy

OrganismRana dybowskii [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide27-33

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus epidermidis ATCC12228

Activity60 μg/mL

MethodMIC

RECORD: Rec_0312363 VERIFIED: YES

Provenance & Taxonomy

OrganismRana dybowskii [Animal]

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermCyclization

Disulfide27-33

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Hemolytic

Targethuman red blood cells

RECORD: Rec_0342846 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anticancer Anti-Gram-positive Anti-Gram-negative

RECORD: Rec_0368361 VERIFIED: YES

Provenance & Taxonomy

OrganismRana dybowskii [Animal]

FamilyBrevinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive

TargetStaphylococcus aureus

Activity15 μM

MethodMIC

RECORD: Rec_0400621 VERIFIED: YES

Provenance & Taxonomy

OrganismRana dybowskii [Animal]

FamilyBrevinin

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetStaphylococcus epidermidis

Activity60 μg/mL

MethodMIC

FIRST PREV 1 ... 5 6 7 8 NEXT LAST

Showing 5 records · Page 7 of 8