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MYP_084658
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Basic Information
17BIPHE2-V21A
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
not Standard
17 amino acids
-
contains X representing unresolved or non-standard residue
Sequence
GXKRLAQRLKDXLRNLV
Physicochemical Analysis
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Residue Composition
Amino Acid Composition
Chemical Descriptors
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0051942 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
biphenylalanine, L at positions 20,24,28 ane D-amino acids instead of L. at 2,12; biphenylalanine, L at positions 20,24,28 ane D-amino acids instead of L.
Bio-Activity Profile
Hemolytic
Human RBC
80 μM
Hemolysis
PMID30800727 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30800727/
RECORD: Rec_0118738 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
biphenylalanine, L at positions 20,24,28 ane D-amino acids instead of L. at 2,12; biphenylalanine, L at positions 20,24,28 ane D-amino acids instead of L.
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Pseudomonas aeruginosa PAO1
6.2 μM
MIC
PMID30800727 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30800727/
RECORD: Rec_0186071 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
biphenylalanine, L at positions 20,24,28 ane D-amino acids instead of L. at 2,12; biphenylalanine, L at positions 20,24,28 ane D-amino acids instead of L.
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Escherichia coli ATCC 25922
3.1-6.2 μM
MIC
PMID30800727 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30800727/
RECORD: Rec_0290612 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
biphenylalanine, L at positions 20,24,28 ane D-amino acids instead of L. at 2,12; biphenylalanine, L at positions 20,24,28 ane D-amino acids instead of L.
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Klebsiella pneumoniae
12.5 μM
MIC
PMID30800727 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30800727/
RECORD: Rec_0411143 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
biphenylalanine, L at positions 20,24,28 ane D-amino acids instead of L. at 2,12; biphenylalanine, L at positions 20,24,28 ane D-amino acids instead of L.
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
Staphylococcus aureus USA300
3.1 μM
MIC
PMID30800727 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30800727/