Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC370H558N84O118S3

DescriptionStandard

        DQVLSLDLPLTSEPVIEASSLNLGLKGEFYSIKTHKEPPFESQPFTMPEQPGYMLSVGMSDFTLNTASYGYYSA
    

Molecular Weight8167.08 Da

Isoelectric Point (pI)4.25

Net Charge (pH 7.0)-6.14

Net Charge (pH 7.4) -6.42

Charge Density (pH 7.0) -0.0830

GRAVY Index-0.23

Hydrophobic Moment 0.30

Boman Index0.14

Instability Index69.44

Aliphatic Index 73.78

Aromaticity 0.1216

Extinction Coeff. Reduced 7450.00

Extinction Coeff. Oxidized 7450.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3188.58

LogP -30.66

H-bond Donors 106.0

H-bond Acceptors 116.0

Rotatable Bonds 258.0

Heavy Atoms 575.0

Ring Count 17.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0060556 VERIFIED: YES

Provenance & Taxonomy

OrganismEtroplus suratensis (Green chromide) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria