Peptide Database

Peptide NameNeuropeptide PF4

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length7 amino acids

Chemical FormulaC45H68N12O9

DescriptionStandard

        KPNFIRF
    

Molecular Weight921.10 Da

Isoelectric Point (pI)11.00

Net Charge (pH 7.0)1.76

Net Charge (pH 7.4) 1.55

Charge Density (pH 7.0) 0.2513

GRAVY Index-0.49

Hydrophobic Moment 0.47

Boman Index-0.13

Instability Index-23.67

Aliphatic Index 55.71

Aromaticity 0.2857

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 360.14

LogP -1.39

H-bond Donors 12.0

H-bond Acceptors 11.0

Rotatable Bonds 28.0

Heavy Atoms 66.0

Ring Count 3.0

Amide Bonds 7.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0069649 VERIFIED: NO

Provenance & Taxonomy

OrganismAscaris suum [Animal]

FamilyFMRFamide related peptide

Tax ID6253

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0109966 VERIFIED: NO

Provenance & Taxonomy

OrganismCaenorhabditis elegans [Animal]

FamilyNeuropeptide PF4

Tax ID6239

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

-

Half-LifeMammalian: 1.3 hour; Yeast: 3 min; E. coli: 2 min

RECORD: Rec_0249808 VERIFIED: NO

Provenance & Taxonomy

OrganismPanagrellus redivivus [Animal]

FamilyFMRFamide related peptide

Tax ID6233

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0292861 VERIFIED: NO

Provenance & Taxonomy

OrganismPanagrellus redivivus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0341763 VERIFIED: NO

Provenance & Taxonomy

Organismnot reported [other]

FamilyFMRFamide-like peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/