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MYP_084535
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Basic Information
Dermaseptin-AC4, DRP-AC4
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
27 amino acids
C120H201N35O35S
Standard
Sequence
SLWGKLKEMAAAAGKAALNAVNGLVNQ
Physicochemical Analysis
2726.16 Da
9.70
1.46
1.25
0.0541
0.22
0.48
0.19
-1.81
105.19
0.0370
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1143.66
-11.85
38.0
38.0
93.0
191.0
2.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0098639 VERIFIED: YES
Provenance & Taxonomy
Agalychnis callidryas [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis NCTC 12697
32 μM
MIC
PMID32397600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32397600/
RECORD: Rec_0126368 VERIFIED: YES
Provenance & Taxonomy
Agalychnis callidryas [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hemolytic
Horse erythrocytes
10 % Hemolysis
Hemolysis
PMID32397600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32397600/
RECORD: Rec_0142594 VERIFIED: YES
Provenance & Taxonomy
Agalychnis callidryas [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Enterococcus faecalis NCTC 12697
64 μM
MBC
PMID32397600 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/32397600/
RECORD: Rec_0203780 VERIFIED: YES
Provenance & Taxonomy
Agalychnis callidryas [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
biofilm formation of Staphylococcus aureus, not great in biofilm eradication
>256 μM
MBEC
PaperIdentification and Rational Design of a Novel Antibacterial Peptide Dermaseptin-AC From the Skin Secretion of the Red-Eyed Tree Frog Agalychnis callidryas
RECORD: Rec_0222569 VERIFIED: YES
Provenance & Taxonomy
Agalychnis callidryas [Animal]
Dermaseptin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
MRSA
32 μM
MIC
PaperIdentification and Rational Design of a Novel Antibacterial Peptide Dermaseptin-AC From the Skin Secretion of the Red-Eyed Tree Frog Agalychnis callidryas
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