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MYP_084526
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Basic Information
Cliotide T4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antiparasitic ▸ Anthelminthic
Antiparasitic ▸ Anthelminthic ▸ Nematicidal activity
Insecticidal/Pest control ▸ Insecticidal activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
30 amino acids
C132H216N36O39S6
Standard
Sequence
GIPCGESCVFIPCITAAIGCSCKSKVCYRN
Physicochemical Analysis
3123.73 Da
8.33
1.70
1.40
0.0567
0.66
0.28
0.20
18.66
78.00
0.0667
1490.00
1865.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1185.12
-13.71
47.0
47.0
98.0
213.0
4.0
30.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0396751 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-20, 8-22, 13-27
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer
PMID21596752 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21596752/
RECORD: Rec_0399384 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Cyclotide
43366
Structure & Mods
Backbone-cyclized cyclotide scaffold with cystine-knot family annotation [Cyclic]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Klebsiella pneumonia ATCC 13883
5.5 μM
MIC
PMID21596752 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21596752/
RECORD: Rec_0411102 VERIFIED: YES
Provenance & Taxonomy
Clitoria ternatea [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
4-20, 8-22, 13-27
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Anticancer Hemolytic
human red blood cells
PMID21596752 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21596752/
RECORD: Rec_0412045 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antibacterial Anticancer Toxic Anti-Gram-positive Cytotoxic Anti-Gram-negative
PaperAPD2: the updated antimicrobial peptide database and its application in peptide design PMID18957441 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18957441/
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