Peptide Database

Peptide NameSLAY-screened peptide P3009

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC111H158N26O27S

DescriptionStandard

        RCAPPINFPTSPPYLFYISH
    

Molecular Weight2320.66 Da

Isoelectric Point (pI)8.21

Net Charge (pH 7.0)0.84

Net Charge (pH 7.4) 0.56

Charge Density (pH 7.0) 0.0418

GRAVY Index-0.07

Hydrophobic Moment 0.27

Boman Index0.21

Instability Index78.78

Aliphatic Index 63.50

Aromaticity 0.2000

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 807.09

LogP -4.92

H-bond Donors 27.0

H-bond Acceptors 30.0

Rotatable Bonds 60.0

Heavy Atoms 165.0

Ring Count 10.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0225255 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/