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MYP_084470
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Anti-HIV ▸ Anti-HIV-1
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
41 amino acids
C223H337N59O76
Standard
Sequence
EWDREINNYTSLIHSLIEESQNQQEKNEQELLELDKWASLW
Physicochemical Analysis
5060.41 Da
4.22
-7.06
-7.29
-0.1721
-1.18
0.58
-0.17
54.94
88.05
0.0976
17990.00
17990.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2256.41
-20.39
75.0
70.0
174.0
358.0
8.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020719 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperHIPdb: a database of experimentally validated HIV inhibiting peptides PMID23359817 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23359817/
RECORD: Rec_0117859 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
HIV-1:inhibition of cell-cell fusion between CHO-WT cells and K652 cells
0.0015±0.0001 μM
IC50
PaperPubMed PMID: 22770564 PMID22770564 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22770564/
RECORD: Rec_0126746 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperPubMed PMID: 22770564 PMID22770564 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22770564/
RECORD: Rec_0342686 VERIFIED: YES
Provenance & Taxonomy
Human immunodeficiency virus 1 [Virus]
11676
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
PEGylation reported in source
Bio-Activity Profile
Antiviral Fusion inhibitor
CHO-WT
0.0015 μM
IC50
PaperSite-Specific PEGylation of HR2 Peptides: Effects of PEG Conjugation Position and Chain Length on HIV-1 Membrane Fusion Inhibition and Proteolytic Degradation. PMID22770564 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22770564/
RECORD: Rec_0354225 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cathelicidin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral
HIV-1
PMID22770564 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22770564/
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