Peptide Database

Peptide NameGambicin (Insects, animals)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Antiparasitic ▸ General antiparasitic ▸ Antiparasitic

Standard StatusStandard

Sequence Length61 amino acids

Chemical FormulaC289H449N83O87S9

DescriptionStandard

        MVFAYAPTCARCKSIGARYCGYGYLNRKGVSCDGQTTINSCEDCKRKFGRCSDGFITECFL
    

Molecular Weight6766.75 Da

Isoelectric Point (pI)8.69

Net Charge (pH 7.0)3.42

Net Charge (pH 7.4) 3.07

Charge Density (pH 7.0) 0.0561

GRAVY Index-0.20

Hydrophobic Moment 0.73

Boman Index-0.05

Instability Index41.39

Aliphatic Index 48.03

Aromaticity 0.1311

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 6460.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2772.64

LogP -32.52

H-bond Donors 108.0

H-bond Acceptors 100.0

Rotatable Bonds 222.0

Heavy Atoms 468.0

Ring Count 9.0

Amide Bonds 63.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0303139 VERIFIED: YES

Provenance & Taxonomy

OrganismAnopheles gambiae [Animal]

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative

TargetPlasmodium berghei

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