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MYP_084462
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Basic Information
Gambicin (Insects, animals)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Standard
61 amino acids
C289H449N83O87S9
Standard
Sequence
MVFAYAPTCARCKSIGARYCGYGYLNRKGVSCDGQTTINSCEDCKRKFGRCSDGFITECFL
Physicochemical Analysis
6766.75 Da
8.69
3.42
3.07
0.0561
-0.20
0.73
-0.05
41.39
48.03
0.1311
5960.00
6460.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2772.64
-32.52
108.0
100.0
222.0
468.0
9.0
63.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0141055 VERIFIED: YES
Provenance & Taxonomy
Insecta [Animal]
50557
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PMID20259524 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/20259524/
RECORD: Rec_0142900 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive Anti-Gram-negative
Neurospora crassa
PMID11606751 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11606751/
RECORD: Rec_0158381 VERIFIED: YES
Provenance & Taxonomy
Anopheles gambiae [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antiparasitic
Micrococcus luteus
25-50 μM
MIC
PaperGambicin: a novel immune responsive antimicrobial peptide from the malaria vector Anopheles gambiae
RECORD: Rec_0184459 VERIFIED: YES
Provenance & Taxonomy
Anopheles albimanus [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
9-20, 12-32, 41-51, 44-59
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiparasitic
crassa
PMID11606751 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11606751/
RECORD: Rec_0287152 VERIFIED: YES
Provenance & Taxonomy
Anopheles albimanus [Animal]
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
9-20, 12-32, 41-51, 44-59
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal Antiparasitic
Escherichia coli
6.25-12.5 μM
MIC
PMID11606751 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11606751/
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