Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length90 amino acids

Chemical FormulaC423H715N127O120S7

DescriptionStandard

        MLPDRSSAPSGNIKLLLLALAVLVVLAQASPDGWLRKCAYGLGKCRKSCKADERKKEKCGRSLSCCVSSTKAKLSHFPKKKNGTGEGLYR
    

Molecular Weight9724.44 Da

Isoelectric Point (pI)9.90

Net Charge (pH 7.0)12.52

Net Charge (pH 7.4) 12.14

Charge Density (pH 7.0) 0.1392

GRAVY Index-0.33

Hydrophobic Moment 0.58

Boman Index-0.12

Instability Index37.00

Aliphatic Index 82.44

Aromaticity 0.0444

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4008.48

LogP -43.81

H-bond Donors 149.0

H-bond Acceptors 141.0

Rotatable Bonds 336.0

Heavy Atoms 677.0

Ring Count 10.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0029293 VERIFIED: NO

Provenance & Taxonomy

OrganismSciurus vulgaris [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence