Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length281 amino acids

Chemical FormulaC1324H2143N411O398S20

DescriptionStandard

        MKAFSIAVAVTLVLAFICVLQSSASPFTGVGELEEAGGNDTPVEAHQEVSLESWMMPKHVREKRQSHLSLCRYCCNCCKNKGCGFCCSGLLRRMDGGGNEGEPPTQTSHPAVPSPGTVQHLESGSKEAASTPVNHNDLQPFLQVTIRVYLFKMSDWFFVIVPVLGSESRLGCVISRLFCRVCVCSATRHPGLLRALTFNLPRLSSSSCGLRVHAPDLQVRGARCTRPTHAGEHRHASLDLTQRRLERKQSKKLRRKTGREGKEIDRKRGEGKDEDGGSGSE
    

Molecular Weight30827.99 Da

Isoelectric Point (pI)9.09

Net Charge (pH 7.0)11.36

Net Charge (pH 7.4) 10.31

Charge Density (pH 7.0) 0.0404

GRAVY Index-0.39

Hydrophobic Moment 0.72

Boman Index-0.09

Instability Index57.69

Aliphatic Index 73.17

Aromaticity 0.0498

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0047422 VERIFIED: NO

Provenance & Taxonomy

OrganismGambusia affinis [Animal]

FamilyHepcidin family

Tax ID33528

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic

MethodQualitative functional evidence