Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length513 amino acids

Chemical FormulaC2607H4054N644O751S20

DescriptionStandard

        MLPRLEMHTKAVQFLWGCFFLWNLCISSTQTIYPGIKARVTQRALDYGIQAGMEMIEQMIKEKNIPDLKGSESLEFLKVDYVNYNFSNIKINAFSFPNTSLAFVPGVGIKALTNHGTANISTNWDVKSPLFQDTGEADLFLSGVYFTGIIVLSQNDFGHPILKLQDCYAQVSHAHVSFSGELSVLYNSFAEPMEKPILKNLNEMLCPIITSEVEALNANLSMLEVLTKIDNYTLLDYSLISSPEITENYIELNLKGVFYPLDNLTDPPFLPVPFALPERSDSMLYVGISEFFFKSASFAYFIAGAFNITLSMKEISNHLVQNSQGLGNMLSRIAEIYILSQPFMVRVMATEPPVISLLPGNFTLDIPASIVILTQPENSTAEAIVSMDFVASTSVGLVILGQRLVCSLSLNRFRLSLPESSRSNIEVLRFENILSSILHFGILPLANAKLQQGIPLPNPHKISFVNSDVEVFEGFLLISTDLKYETSLKQQPSFHGWEGLSLMSGQWRGKPAA
    

Molecular Weight57075.24 Da

Isoelectric Point (pI)5.10

Net Charge (pH 7.0)-14.69

Net Charge (pH 7.4) -15.56

Charge Density (pH 7.0) -0.0286

GRAVY Index0.19

Hydrophobic Moment 0.68

Boman Index0.19

Instability Index38.88

Aliphatic Index 103.76

Aromaticity 0.1033

Extinction Coeff. Reduced 49850.00

Extinction Coeff. Oxidized 50100.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0174770 VERIFIED: NO

Provenance & Taxonomy

OrganismNyctereutes procyonoides (Raccoon dog) [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria