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MYP_084332
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Basic Information
Brevinin-1BYa [C18S,C24S]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
24 amino acids
C126H206N28O29
Standard
Sequence
FLPILASLAAKFGPKLFSLVTKKS
Physicochemical Analysis
2577.15 Da
10.48
3.76
3.55
0.1565
0.80
0.53
0.30
18.56
122.08
0.1250
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
900.04
-4.21
31.0
33.0
84.0
183.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0350795 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus aureus ATCC 25923
3 μM
MIC
PMID21312033;16713189 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
RECORD: Rec_0378533 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID21312033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
RECORD: Rec_0399077 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Staphylococcus epidermidis RP62A
5 μM
MIC
PMID21312033;16713189 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
RECORD: Rec_0425365 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida tropicalis B51a/5
10 μM
MIC
PMID21312033;16713189 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
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