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MYP_084332
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Basic Information
Brevinin-1BYa [C18S,C24S]
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
24 amino acids
C126H206N28O29
Standard
Sequence
FLPILASLAAKFGPKLFSLVTKKS
Physicochemical Analysis
2577.15 Da
10.48
3.76
3.55
0.1565
0.80
0.53
0.30
18.56
122.08
0.1250
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
900.04
-4.21
31.0
33.0
84.0
183.0
5.0
23.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0194791 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
MDA-MB-231
13 μM
LC50
PMID21312033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
RECORD: Rec_0195443 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida tropicalis
20 μM
MIC
PMID21312033;16713189 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
RECORD: Rec_0206947 VERIFIED: YES
Provenance & Taxonomy
Synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
side-chain cyclized/stapled peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
Human erythrocytes
75 μM
LC50
PMID21312033 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
RECORD: Rec_0223131 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Candida parapsilosis
40 μM
MIC
PMID21312033;16713189 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
RECORD: Rec_0223697 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
Human breast adenocarcinoma MDA-MB-231
13 μM
LC50
PMID21312033;16713189 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21312033/
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