Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length220 amino acids

Chemical FormulaC1102H1724N268O318S8

DescriptionStandard

        QIDAFAQIDYSLISSPTVFKSHINLDLKGTVYPVGNHTDPPFVPAPFDLPDQGDSMLYLGVSSYFLKSASLAYYRAGAFNITISEEEKVNSAFNIFFLFEIPQVALSYVTACPVLLKLMATSPPAVSLNADRCMLHITGCVEMFAVLPNSTTQYIFTGNLTASTRANLTITKQKLIISLLLKRLQFSLLHSTLGSSEMSLVENFLSYALQSAVIPVINGK
    

Molecular Weight24071.60 Da

Isoelectric Point (pI)6.07

Net Charge (pH 7.0)-1.91

Net Charge (pH 7.4) -2.40

Charge Density (pH 7.0) -0.0087

GRAVY Index0.36

Hydrophobic Moment 0.45

Boman Index0.23

Instability Index47.36

Aliphatic Index 105.95

Aromaticity 0.1045

Extinction Coeff. Reduced 13410.00

Extinction Coeff. Oxidized 13535.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0308690 VERIFIED: NO

Provenance & Taxonomy

OrganismNyctiprogne leucopyga [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria