Peptide Database

Peptide NameLantibiotic mutacin-1140 (Mutacin III)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC299H452N76O106S5

DescriptionStandard

        MSNTQLLEVLGTETFDVQEDLFAFDTTDTTIVASNDDPDTRFKSWSLCTPGCARTGSFNSYCC
    

Molecular Weight6967.56 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-7.53

Net Charge (pH 7.4) -7.81

Charge Density (pH 7.0) -0.1194

GRAVY Index-0.26

Hydrophobic Moment 0.31

Boman Index0.03

Instability Index19.71

Aliphatic Index 55.71

Aromaticity 0.1111

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2947.91

LogP -37.48

H-bond Donors 106.0

H-bond Acceptors 104.0

Rotatable Bonds 222.0

Heavy Atoms 486.0

Ring Count 10.0

Amide Bonds 67.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0031441 VERIFIED: YES

Provenance & Taxonomy

OrganismStreptococcus mutans [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram Positive Bacteria

RECORD: Rec_0050870 VERIFIED: NO