Peptide Database

Peptide NameHuman beta defensin 3

Function Ontology

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Standard StatusStandard

Sequence Length37 amino acids

Chemical FormulaC169H282N56O52S4

DescriptionStandard

        GIINTLQRYYCQIRGGRCALVSCLPREEQIGRCSSGG
    

Molecular Weight4058.65 Da

Isoelectric Point (pI)8.94

Net Charge (pH 7.0)2.72

Net Charge (pH 7.4) 2.46

Charge Density (pH 7.0) 0.0736

GRAVY Index-0.21

Hydrophobic Moment 0.64

Boman Index-0.08

Instability Index53.99

Aliphatic Index 84.32

Aromaticity 0.0541

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1779.97

LogP -22.16

H-bond Donors 68.0

H-bond Acceptors 59.0

Rotatable Bonds 136.0

Heavy Atoms 281.0

Ring Count 3.0

Amide Bonds 40.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0407301 VERIFIED: YES

Provenance & Taxonomy

OrganismAiluropoda melanoleuca [Animal]

FamilyDefensin

Structure & Mods

ConfigDNA-encoded linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)