Peptide Database

Peptide NameSLAY-screened peptide P1409

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length9 amino acids

Chemical FormulaC38H67N11O16S

DescriptionStandard

        TMKINASSD
    

Molecular Weight966.07 Da

Isoelectric Point (pI)5.75

Net Charge (pH 7.0)-0.60

Net Charge (pH 7.4) -0.79

Charge Density (pH 7.0) -0.0665

GRAVY Index-0.56

Hydrophobic Moment 0.12

Boman Index-0.11

Instability Index20.86

Aliphatic Index 54.44

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 463.22

LogP -7.06

H-bond Donors 16.0

H-bond Acceptors 17.0

Rotatable Bonds 33.0

Heavy Atoms 66.0

Ring Count 0.0

Amide Bonds 9.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0370691 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/