Peptide Database

Peptide NameMelittin (MEL) (MLT)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Venom / Toxin ▸ General toxin ▸ Toxin

Standard StatusStandard

Sequence Length70 amino acids

Chemical FormulaC347H548N84O97S2

DescriptionStandard

        MKFLVNVALVFMVVYISFIYAAPEPEPAPEAEAEADAEADPEAGIGAVLKVLATGLPALISWIKRKRQQG
    

Molecular Weight7512.70 Da

Isoelectric Point (pI)4.69

Net Charge (pH 7.0)-3.48

Net Charge (pH 7.4) -3.72

Charge Density (pH 7.0) -0.0498

GRAVY Index0.38

Hydrophobic Moment 0.57

Boman Index0.24

Instability Index46.47

Aliphatic Index 108.86

Aromaticity 0.0857

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8480.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2828.27

LogP -17.56

H-bond Donors 93.0

H-bond Acceptors 96.0

Rotatable Bonds 240.0

Heavy Atoms 530.0

Ring Count 13.0

Amide Bonds 72.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0207476 VERIFIED: YES

Provenance & Taxonomy

OrganismPolistes hebraeus [Animal]

FamilyMelittin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Cytolytic Toxin Hemolytic