Peptide Database

Peptide NameHepcidin

Function Ontology

—

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC85H143N25O23S9

DescriptionStandard

        ICLFCCGCCNKPMCGLCCRT
    

Molecular Weight2171.78 Da

Isoelectric Point (pI)8.22

Net Charge (pH 7.0)1.68

Net Charge (pH 7.4) 1.36

Charge Density (pH 7.0) 0.0840

GRAVY Index1.09

Hydrophobic Moment 0.29

Boman Index0.19

Instability Index23.43

Aliphatic Index 58.50

Aromaticity 0.0500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 500.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 758.67

LogP -8.40

H-bond Donors 34.0

H-bond Acceptors 34.0

Rotatable Bonds 68.0

Heavy Atoms 142.0

Ring Count 2.0

Amide Bonds 20.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0062146 VERIFIED: YES

Provenance & Taxonomy

OrganismLeptonychotes weddellii [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)