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MYP_084157
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Basic Information
As-CATH4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
38 amino acids
C205H359N67O40
Standard
Sequence
RRGLFKKLRRKIKKGFKKIFKRLPPVGVGVSIPLAGRR
Physicochemical Analysis
4402.47 Da
12.00
14.75
14.54
0.3882
-0.49
0.94
-0.30
53.31
97.37
0.0789
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1775.34
-12.08
66.0
55.0
156.0
312.0
6.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0161259 VERIFIED: YES
Provenance & Taxonomy
Alligator sinensis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Vibrio vulnificus
1.07
MIC
PMID29017942 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29017942/
RECORD: Rec_0183066 VERIFIED: YES
Provenance & Taxonomy
Alligator sinensis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-negative
Aeromonas hydrophila
2.13 μM
MIC
PMID29017942 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29017942/
RECORD: Rec_0204723 VERIFIED: YES
Provenance & Taxonomy
Alligator sinensis [Animal]
Cathelicidin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal Anti-Gram-positive
Staphylococcus aureus
4.26 μM
MIC
RECORD: Rec_0250579 VERIFIED: YES
Provenance & Taxonomy
Alligator sinensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer
BGC-823
26±0.9 %
Cytotoxicity
PaperPubMed PMID: 28798159 PMID28798159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28798159/
RECORD: Rec_0257026 VERIFIED: YES
Provenance & Taxonomy
Alligator sinensis [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PaperPubMed PMID: 28798159 PMID28798159 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/28798159/
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