Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length435 amino acids

Chemical FormulaC2171H3440N562O620S13

DescriptionStandard

        MAILQKELEKIKIPDFSGSFQIKHLGTGHYSFYSMAIHRFQLPHSQMTLVPNVGLKLSTSNANLKIIGKWKAQKNFLKASGNFDVSVEGISVSADLKVGSDLSSGHATIACSNCSNSISSVHVDISGSHLGWLIKLFHKKIESSLRKVMNSKICEVVTSIVASKLQPYFQTLPVTAKIDEVAGIDYSLVAPPAASADSLDVQLKGEFFRLAHRTPPPFVPSALTFPTDHNRMVYLGISDYFINTAGLVYQEAGVLNLNLTDDMIPKESQFRLTTKFLGSLIPQVARSFPDMKVQLLISVSSPPHLSVDPSRLTLTPQLEVQAFAILPNSSLAPLFQLGLSMNVSVEVGAKSNRLVGKLMIDEVHLELKHSDVGPFSVQLLEAIINYFMSSVVLPKVNERLQQGFPLPLLAHIQLDNLLLQSYQDFLLFGADVHYG
    

Molecular Weight47750.77 Da

Isoelectric Point (pI)7.78

Net Charge (pH 7.0)1.81

Net Charge (pH 7.4) 0.70

Charge Density (pH 7.0) 0.0042

GRAVY Index0.15

Hydrophobic Moment 0.72

Boman Index0.15

Instability Index32.09

Aliphatic Index 106.41

Aromaticity 0.0805

Extinction Coeff. Reduced 25900.00

Extinction Coeff. Oxidized 26025.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0322093 VERIFIED: NO

Provenance & Taxonomy

OrganismChrysochloris asiatica [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria