Peptide Database

Peptide NameD2A21

Function Ontology

Anticancer

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antiviral

Antiviral ▸ Anti-Retrovirus ▸ Anti-Lentivirus ▸ Anti-FIV

Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition

Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition ▸ Release inhibitor

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length23 amino acids

Chemical FormulaC144H212N32O24

DescriptionStandard

        FAKKFAKKFKKFAKKFAKFAFAF
    

Molecular Weight2775.42 Da

Isoelectric Point (pI)10.90

Net Charge (pH 7.0)8.75

Net Charge (pH 7.4) 8.53

Charge Density (pH 7.0) 0.3805

GRAVY Index-0.08

Hydrophobic Moment 0.83

Boman Index-0.01

Instability Index3.03

Aliphatic Index 26.09

Aromaticity 0.3478

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 937.70

LogP -0.71

H-bond Donors 33.0

H-bond Acceptors 33.0

Rotatable Bonds 97.0

Heavy Atoms 200.0

Ring Count 8.0

Amide Bonds 22.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0419063 VERIFIED: NO

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyFLAK peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermAmidation

Bio-Activity Profile

Function

Anticancer Cytotoxic

TargetHeLa

Activity170 μg/mL

MethodLD50

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