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MYP_084101
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Basic Information
D2A21
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Antimicrobial ▸ Antibacterial
Antiviral
Antiviral ▸ Anti-Retrovirus ▸ Anti-Lentivirus ▸ Anti-FIV
Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition
Antiviral ▸ Antiviral mechanism ▸ Viral release inhibition ▸ Release inhibitor
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
23 amino acids
C144H212N32O24
Standard
Sequence
FAKKFAKKFKKFAKKFAKFAFAF
Physicochemical Analysis
2775.42 Da
10.90
8.75
8.53
0.3805
-0.08
0.83
-0.01
3.03
26.09
0.3478
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
937.70
-0.71
33.0
33.0
97.0
200.0
8.0
22.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0288194 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Chlamydia trachomatis
2.5 μM
PMID11751108;32204024 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11751108/
RECORD: Rec_0295298 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Anticancer
PaperAntiCP 2.0: an updated model for predicting anticancer peptides (benchmark provenance; exact sequence-level experiment paper unresolved here) | https://pubmed.ncbi.nlm.nih.gov/32770192/
RECORD: Rec_0301524 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Cryptococcus neoformans ATCC 32045
21.9 μg/mL
IC50
PMID11751108;32204024 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11751108/
RECORD: Rec_0326840 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Brevinin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli ATCC 25922
12.5 μM
MBC
PMID11751108;32204024 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/11751108/
RECORD: Rec_0336969 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Release inhibitor
Feline immunodeficiency virus (Release); CrFK
3.05 μM
RT-PCR
PaperInhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro. | Ma J, Kennedy-Stoskopf S, Jaynes JM, Thurmond LM, Tompkins WA. | J Virol. 2002 | PMID:12208971 PMID12208971 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12208971/
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