Peptide Database

Peptide NameDefensin 5 (Enteric defensin) (RD-5)

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length93 amino acids

Chemical FormulaC444H734N124O136S8

DescriptionStandard

        MKKLVLLSALVLLALQVEAEPTPKTDEGTKTDEQPGKEDQVVSVSIEGQGDPAFQDAVLRDLKCFCRRKSCNWGEGIMGICKKRYGSPILCCR
    

Molecular Weight10241.85 Da

Isoelectric Point (pI)7.54

Net Charge (pH 7.0)0.46

Net Charge (pH 7.4) 0.12

Charge Density (pH 7.0) 0.0049

GRAVY Index-0.27

Hydrophobic Moment 0.83

Boman Index-0.06

Instability Index40.72

Aliphatic Index 85.91

Aromaticity 0.0430

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4201.78

LogP -41.77

H-bond Donors 149.0

H-bond Acceptors 145.0

Rotatable Bonds 350.0

Heavy Atoms 712.0

Ring Count 10.0

Amide Bonds 98.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0222542 VERIFIED: YES

Provenance & Taxonomy

OrganismRattus norvegicus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10116

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic