Peptide Database

Peptide NameColicin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Enzyme / Catalytic activity ▸ Hydrolase ▸ Nuclease

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length582 amino acids

Chemical FormulaC2687H4253N803O872S10

DescriptionStandard

        MSGGDGIGHSSGAHATGGVNGSSSGSGGSSSGGGNNPNSGPGWGTTHTPNGDIHNYNPGEFGGGGHKPGGNSGNHDSGSGNGQPSGTVMAFGFPALAPAGAGGLAVTVSGDALAAAIADVLAALKGPFKFGTWGIALYGIMPTEIAKDDPSMMSKIVTSLPVDTVTESPVSSLPLDQATVSVTKRVTDVVKDERQHIAVVAGVPMSVPVVDAKPTNTPGVFSATVPGLPALEVSTGKDIPASTALPRGITEDKDRTERPAGFTFGGSSHEAVIRFPKESGQAPVYVSVTDVLTPEQVKQRQEEENRRQQEWDATHPVEVAERNYRLASDELNRANADVTGKQERQAQAGQAVAARKGELDAANKTFAEAKEEIKKFERFAHDPMAGGHRMWQMAGLKAQRAQNEVNQKQVEFNAAEKEKADADAALNEALENRKQKEQKAKDTKDKLDKENKRNQSGTATGQGQPVGDKWLEDASKEAGAPVPDRIADKLRGKEFRDFDDFRKKFWEEVSKDPELRKQFRKNNQKLIEKGNAPYPVPEEQVGGRETFELHHVKPISQDGGVYDMDNLRVTTPKRHIDIHRGK
    

Molecular Weight62079.02 Da

Isoelectric Point (pI)6.15

Net Charge (pH 7.0)-6.08

Net Charge (pH 7.4) -7.23

Charge Density (pH 7.0) -0.0104

GRAVY Index-0.74

Hydrophobic Moment 0.75

Boman Index-0.10

Instability Index40.07

Aliphatic Index 60.72

Aromaticity 0.0533

Extinction Coeff. Reduced 41940.00

Extinction Coeff. Oxidized 41940.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0377897 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella enterica subsp. salamae serovar 55:k:z39 str. 1315K [Bacterium]

FamilyColicin/Pyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease

TargetEscherichia coli

RECORD: Rec_0417639 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmonella enterica [Bacterium]

FamilyColicin/Bacteriocin

Tax ID28901

Structure & Mods

Configlinear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Endonuclease Hydrolase Nuclease Non-hemolytic

TargetEscherichia coli (Gram-negative)

MethodQualitative functional evidence