Peptide Database

Peptide NameAlpha-defensin 11 (Defensin-related cryptdin-11)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length85 amino acids

Chemical FormulaC399H645N119O136S8

DescriptionStandard

        ALVLLAFQVQADPIQNTDEETKTEEQPGEEDQAVSVSFGDPEGTSLQEESLRDLVCYCRSRGCKGRERMNGTCRKGHLLYMLCCR
    

Molecular Weight9541.63 Da

Isoelectric Point (pI)4.78

Net Charge (pH 7.0)-5.15

Net Charge (pH 7.4) -5.50

Charge Density (pH 7.0) -0.0606

GRAVY Index-0.63

Hydrophobic Moment 0.59

Boman Index-0.16

Instability Index49.04

Aliphatic Index 67.65

Aromaticity 0.0471

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4168.37

LogP -49.23

H-bond Donors 149.0

H-bond Acceptors 140.0

Rotatable Bonds 325.0

Heavy Atoms 662.0

Ring Count 8.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0249195 VERIFIED: YES

Provenance & Taxonomy

OrganismMus musculus [Animal]

FamilyAlpha-defensin; Defensin

Tax ID10090

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic

TargetNo Target Organism Found