Peptide Database

Peptide NameType VI secretion system tip protein VgrG

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length1194 amino acids

Chemical FormulaC5837H9100N1672O1790S36

DescriptionStandard

        MMDNRSAFFDGQTRYFLEINGSAVKSDVLRFRGREALSEPFRWDIGFTSRNANIPPEEVLMKYASLRMRNGKNVHGIVTRLEWLSTSKDQSHYRLTLSSRLALLEHTRQCAVFQNQSVPEVVEQVLRKHGLEGADFEFRLERAYPSREIITQWQETDLQFIQRILSEVGIYWRTEMDDVRGLDTYIFADSQLHYQFDVQLPYSEPSGLFDGAAESVWDVRTWHNVATGTVTTRDYNYRTAATPMNATVSVRNDAVTTGEHYRDAPAYREAGDDASPEPETESGAFYARLHHERELNRSARIHLFSNAAHLSPGQVLEPQGDVITDLKEGIVLTLVTYRGARDTRLHVSARGMPYTERYCFRPAEIPRPVIPGTLPARIESREKNDIYAHLDGQGRYRVKMDFDREETEPGYGYLWLRMAKPCAGETLGWHTPLIDGTEVAIAYSNGDIDLPYIAYALHDAEHPDPVNRDNHTRNILRTPANSKLRMEDRRGEEHIKLATEYGKTQLNSGHLVDSQGQLRGKGTELRTDEWGTLRAGKGLFVAADAQAKAQGEALDMDAALKEIDRLNQQLQQLENAAERAQALKADIDSQRQMFEQRLKPLNEALVFSAPEGMALTSGEDMQMSAARNVAVNAGGDISTGTMGNLTALAGEKLGLFARTGQLSAKSGEGPVEVQAQNGSMRLFAEKKLTLSSASDISFAGKKRITLIGGGSYLRLEAGKVEYGTTAKYLRKVKRTMAASASSEAAQTVSLPTPVTMREFNPETLTPWVTPVYAKSCLKEKGCTDAGTAEEPVEHFGQMTIFAQPVVDDCCGYGHQHEHTDDEVVQHAQSARKRKPDIGGAKAPAPTGATAAPLALGAATGVMTQVWGEWSLTGVLGAARGIPYIGAMMSALYVPSAGEGSDRVPGRDEFWYEEELWQKALTGAKATTRVRFFWRQDEQGNMRVYGVHTGEGTPYEGVRTANMVWNSQNNRYEFTPAHGADGLLITWTPERPEGSDLPSHTGSGIKLPDQATILVTPIPDGKDEYTTSPFPVPEERDFNDYILVFPAGSGIKPIYVYLKTARDEPGVATGKGKILSGSEKWLEAASSGLGAPVPAQVASKLRGKSFRNFDHFREEFWLAVSECPELMKDFKPSNQILIRMGLAPYPVPSEQVGGRTTFELHHLEEIQHGGEVFNMDNINVTTPRLHIGIHKNANR
    

Molecular Weight132491.17 Da

Isoelectric Point (pI)5.83

Net Charge (pH 7.0)-21.46

Net Charge (pH 7.4) -23.79

Charge Density (pH 7.0) -0.0180

GRAVY Index-0.51

Hydrophobic Moment 0.80

Boman Index-0.04

Instability Index34.82

Aliphatic Index 73.34

Aromaticity 0.0829

Extinction Coeff. Reduced 164100.00

Extinction Coeff. Oxidized 164600.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0093157 VERIFIED: YES

Provenance & Taxonomy

OrganismEscherichia coli [Bacterium]

FamilyVgrG protein family

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal

TargetEscherichia coli