Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length99 amino acids

Chemical FormulaC498H821N141O142S10

DescriptionStandard

        MKAFLLTLAALVLLSQVTSGSAEKCWNLRGSCREKCIKNEKLYIFCTSGKLCCLKPKFQPNMLQRNRKDNPKICLEPQKILNIQSNLDKEEQSWKHCTS
    

Molecular Weight11376.36 Da

Isoelectric Point (pI)9.34

Net Charge (pH 7.0)8.51

Net Charge (pH 7.4) 8.10

Charge Density (pH 7.0) 0.0860

GRAVY Index-0.42

Hydrophobic Moment 0.48

Boman Index-0.11

Instability Index51.68

Aliphatic Index 84.75

Aromaticity 0.0606

Extinction Coeff. Reduced 12490.00

Extinction Coeff. Oxidized 12990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4647.64

LogP -45.82

H-bond Donors 166.0

H-bond Acceptors 162.0

Rotatable Bonds 395.0

Heavy Atoms 791.0

Ring Count 13.0

Amide Bonds 111.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0019242 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial

RECORD: Rec_0396913 VERIFIED: NO

Provenance & Taxonomy

OrganismCanis lupus familiaris [Animal]

FamilyDefensin

Tax ID9615

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence