Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length67 amino acids

Chemical FormulaC356H564N98O95S8

DescriptionStandard

        MKIHLFFFILLFCLTVLPARKSYSQYDELDLTRECRKGNGRCKVECQENEIRIAFCIKFATHCCLER
    

Molecular Weight7993.41 Da

Isoelectric Point (pI)8.54

Net Charge (pH 7.0)2.62

Net Charge (pH 7.4) 2.18

Charge Density (pH 7.0) 0.0391

GRAVY Index-0.01

Hydrophobic Moment 0.56

Boman Index-0.04

Instability Index40.51

Aliphatic Index 88.81

Aromaticity 0.1194

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 3355.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3146.36

LogP -23.55

H-bond Donors 118.0

H-bond Acceptors 108.0

Rotatable Bonds 271.0

Heavy Atoms 557.0

Ring Count 11.0

Amide Bonds 70.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0059979 VERIFIED: NO

Provenance & Taxonomy

OrganismErinaceus europaeus [Animal]

FamilyBeta-defensin; Defensin

Tax ID9365

Structure & Mods

Configdisulfide-constrained cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfidedisulfide bond; sites not specified

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic