Peptide Database

Peptide NameSubtilosin-A (Antilisterial bacteriocin subtilosin)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive ▸ Anti-Listeria

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Standard StatusStandard

Sequence Length43 amino acids

Chemical FormulaC193H308N48O56S4

DescriptionStandard

        MKKAVIVENKGCATCSIGAACLVDGPIPDFEIAGATGLFGLWG
    

Molecular Weight4325.06 Da

Isoelectric Point (pI)4.78

Net Charge (pH 7.0)-1.52

Net Charge (pH 7.4) -1.79

Charge Density (pH 7.0) -0.0355

GRAVY Index0.69

Hydrophobic Moment 0.29

Boman Index0.35

Instability Index20.00

Aliphatic Index 97.67

Aromaticity 0.0698

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 5625.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1614.77

LogP -13.95

H-bond Donors 57.0

H-bond Acceptors 59.0

Rotatable Bonds 139.0

Heavy Atoms 301.0

Ring Count 6.0

Amide Bonds 43.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0393376 VERIFIED: YES

Provenance & Taxonomy

OrganismBacillus amyloliquefaciens [Bacterium]

Structure & Mods

ConfigSingle-chain peptide backbone represented as a linear sequence entry [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative

TargetMicrococcus luteus ATCC 10420

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